November 2022

  • Pila Pharma broadens XEN-D0501 with new indication for the treatment of erythromelalgia.The FDA has assigned XEN-D0501 orphan drug designation for treatment of erythromelalgia.XEN-D0501 targets the TRPV1 receptor.Click to access details

October 2022

  • AlgoTx has now announced its Phase 2 global clinical trial of ATX01 in chemotherapy-induced peripheral neuropathy in adults.Results expected late 2024. The novel topical ATX01 has orphan status for erythromelalgia.Click to access details

September 2022

  • Clinical trials of two novel drugs for the treatment of peripheral neuropathy Topical pirenzepine 4% (WST-057) and NRD135S.E1 (Siberian root)   Click to access details

July 2022 

  • Experimental implant uses coolant to numb nerve pain. Could this help EM sufferers in the future? Click to access details
  • New amitriptyline topical ATX01 granted orphan status for erythromelalgia and for other forms of peripheral neuropathy. Phase 2 due to start late 2022.

May 2022

 June 2020/21

  • French start up pharmaceutical excited about new amitriptyline topical ATX01 for erythromelalgia. Clinical trials for this topical due late 2020

April 1st 2019

  • Gabapentin and pregabalin will be classed as controlled drugs in the UK  as from April 1st. See your surgery if concerned.

January 2019

  • The aim of the study is to create a patient registry and learn more about the cause, progression and underlying genetic basis of certain rare diseases – with a particular interest in EM patients/families who do not have the Nav 1.7 mutation. Full details Genetics and Pain Sensitivity Research Program

July 2015

  • Xenon announces follow up to the primary genetic study, which will focus on facial EM. Xenon are currently inviting certain participants from the 2013 genetic study to take part in a survey on facial EM. Participants are being asked to fill in an online questionnaire and provide a saliva sample (if requested). This is fantastic move forward for the EM community! 

August 2015

  • FDA OK a new drug 'Finacea' for Papulopustular Rosacea.

October 2015

  • Xenon are still performing free worldwide genetic testing with saliva kit (Ended 2017)

November 2015

  • 'Tonmya', a drug developed for the treatment of fibromyalgia, could be available end of 2016. For more information

January 2016

  • EM transdermal 'Midodrine' developed by Mayo clinic available through compounding pharmacists.

February 2016

  • IMC-1 promising fibromyalgia drug fast tracked by FDA.

March 2016

  • New findings potentially provide several new drug targets - CSF1, CSF1 receptor, and DAP12 - that have huge therapeutic potential for neuropathic pain.
  • Drug candidate ZYN001 that delivers marijuana via skin patch soon to be developed for fibromyalgia.
  • Beiersdorf study shows licorice extract can help rosacea.
  • CDC release new guidelines for opioid prescribing for chronic pain.

April 2016


What Is Erythromelalgia?




Read more


Inspirational Faces of Erythromelalgia

I Am The Face Of Erythromelalgia Campaign 2022/2023



New Erythromelalgia Topical 2022


The FDA has granted Orphan Drug designation to ATX01 for the treatment of erythromelalgia.
ATX01 is a topical gel formulation of a proprietary high-concentration amitriptyline that works by targeting damaged nerve fibers in the skin, while avoiding systemic adverse reactions. The designation is supported by preclinical studies of topical amitriptyline that showed antinociceptive activity on voltage-gated sodium-channels Nav1.7, Nav1.8 and Nav1.9 as well as peripheral sensory nerve fibers Aβ, A∂ and C.
AlgoTherapeutix is a French biotech start-up, hosted by the Paris Biotech Santé incubator developing ATX01, a treatment for Chemotherapy-Induced Peripheral Neuropathy and Erythromelalgia. https://www.pharmaceutical /news/algotherapeutix-announces-orphan-drug-designation-granted-by-fda-for-atx01-in-erythromelalgia/
The opportunity to investigate ATX01 in erythromelalgia is an exciting medical pursuit as patients have few options to relieve considerable pain
EM Warriors will bring you further news as soon as it is released



The Heart of FACES is You and We Need Your Help. | FACESVA | Family  Advocacy Creating Education and Services ERYTHROMELALGIA WARRIORS FUNDRAISER 2022

All donations over $25 receive a free awareness bracelet or charity ribbon pin



You are fierce
You are a survivor.
You are a fighter through and through.
You are brave, you are courageous
There's an erythromelalgia warrior within YOU!





December 2022                                  

  • USA TODAY has just published an article on the future of pain relief . The article focuses on genetic erythromelalgia (IEM) and congenital insensitivity to pain (CIP) whilst exploring chronic pain, the challenges of treatment and the scientific advances offering hope for the future.



 November 2022

  • Several studies report how researchers have found that green light helps different forms of chronic pain. Could wearing green eye -glasses be a future method of pain relief?                                                    








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EM Warriors Partner With The Mighty

EM Warriors Are Partnering With The Mighty!

We're thrilled to announce a new partnership that will bring our resources in front of The Mighty's wide-reaching readership. We will now have a growing home page on The Mighty and appear on many stories on the site.


The Mighty is a story-based health community focused on improving the lives of people facing disease, disorder, mental illness and disability. More than half of Americans are facing serious health conditions or medical issues. They want more than information. They want to be inspired. The Mighty publishes real stories about real people facing real challenges.


We're dedicated to helping people with erythromelalgia in their lives. With this partnership, we'll be able to help even more people.

We encourage you to submit a story to The Mighty and make the voice of an erythromelalgia sufferer heard.

"Here's an example of the kind of stories on The Mighty: To the Person Who Thinks My Fibromyalgia Isn't Real"

Other story options: 

 Do you want to tell your story but don't know where to begin? Contact us at and we will help you get your story down and published. 




Today's News Highlights

Kristen Zemnickas is now a member of Erythromelalgia Warriors: Patient Support & Information Network
Amy Zink, Nikki Ramsay and Nicky Baker joined Erythromelalgia Warriors: Patient Support & Information Network
Admin Admin team
Jan 22
Belinda Wood is now a member of Erythromelalgia Warriors: Patient Support & Information Network
Jan 9
Hannah updated their profile
Jan 8
Hannah, Debra and James McConn joined Erythromelalgia Warriors: Patient Support & Information Network
Jan 8
Karen Bosnyak updated their profile photo
Dec 15, 2022
Maria Williams is now a member of Erythromelalgia Warriors: Patient Support & Information Network
Dec 12, 2022
Vincent Ramard is now a member of Erythromelalgia Warriors: Patient Support & Information Network
Dec 6, 2022

Pain Research UK


Do you wish you could predict your pain severity in the near future?
Researchers at the University of Manchester are building a 'pain forecast' and are interested in hearing your thoughts about this.
They are conducting a UK-wide questionnaire, and you are invited to fill it out here:
If you would like any more information, please feel free to contact or ask the admin team
Thank you!





The content of the EM Warriors website, including text, graphics, images, information obtained from licensors, and other material, is intended for informational and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.

Please never disregard the advice of your physician or delay seeking it because of something you have read on this website.